either you are running a 3rd party program that is not supported here... or something is messed up with your Winetricks version if shows a blank Window. If you have Zenity installed, then running Winetricks should have a GUI, other wise you have to use it command line. If you are using something like Wineskin, WineBottler (including its Wine.app), PlayOnMac, etc etc... and not normal Wine, then you need to go to those specific websites to get help. Normal Wine on Mac OS X is built from source and run all command line. MacPorts or Fink can make the compiling much easier, but its still command line. Without knowing more of what you actually have, its not easy to tell you where to go for help.