Ok, sorry for cluttering up the winehq forum with a WineBottler question. The startwine script is referenced in an FAQ on his wiki: http://winebottler.kronenberg.org/trac/wiki/WineCmdLine In the latest release, however, startwine or startwine.sh is nowhere to be found. Here's where I found the script, on Mike's blog: http://mike.kronenberg.org/?p=359 I adapted it to my environment by changing a couple variables and some of the quoting, and it works fine. I can invoke it as such: Code: startwine "/Applications/WinXP/drive_c/Program Files/WinMerge/WinMergeU.exe" "Z:\Users\usera" "Z:\Users\userb" Hope this helps future googlers.