I have been experiencing the same problem ever since I upgraded to 1.3.9. ---------------------------------------------------------------------------------------- The program uninstaller.exe has encountered a serious problem and needs to close. We are sorry for the inconvenience. This can be caused by a problem in the program of a deficiency in Wine. You may want to check http://appdb.winehq.org for tips about running this application. If this problem is not present under Windows and has not been reported yet, you can report it at http://bugs.winehq.org. ---------------------------------------------------------------------------------------- This happens every time I attempt to launch the Wine uninstaller. Like the OP I am also running Ubuntu 10.10. I am about to run off and file a bug but I wanted to post this here as well to let everyone know that this is not a problem isolated to a single user. Until I saw this post I was concerned that I was the only one experiencing the problem.