I wanted to follow up with the things I did to get things working. Maybe it will be of help to others... Install WineASIO drivers for your distribution. Register the WineASIO drivers using a command such as: I actually forgot what command I used, but you can Google it... WINE: run `winecfg`, choose Audio tab> Select Alsa driver DirectSound pane: Default Sample Rate: 44100, Default Bits Per Sample: 16 Note: "Test Sound" test may fail if Jack is already running, but sound may still eventually work. If I tried to run the test, it locked up winecfg. The way to unlock it is to quit Jack. Run Jack: Setup> Settings> MIDI Driver: seq Restart Jack for settings to take place. Run Kontakt: `wine 'kontakt 4'` Options> Audio> set Driver to "ASIO", set Device to "Wine ASIO Driver" MIDI> Inputs> Akai MPK88 Midi 1 to Port A Go to Jack "Connections", in Audio tab, connect "ASIO_Kontakt 4" to "system" Note: if you make changes to the audio drivers in winecfg, this may reset the MIDI options in Kontakt, and you will have to redo them. Hope that helps! -Cosmo -- View this message in context: http://wine.1045685.n5.nabble.com/Kontakt-doesn-t-respond-to-Akai-USB-MIDI-Keyboard-tp2640128p2849080.html Sent from the Wine - Users mailing list archive at Nabble.com.