thank you very much daVinci I did it as you said and it works now my question is I want to install bioedit using wine I followed the instructions I got to installed but it not run, to be honest I am not quite sure how to use wine in wine I configure it by adding some files in the library then I put the application in win 98 according to the instructions, after that I download the software bioedit and I extracted it and it looks like I was installing it using windows however it didn't run any idea please