Does ten-tec pegagus let you use telnet? I think serial port access under wine has been flaky in the past, not sure about current version. I use serial port access under wine, using teraterm terminal emulator, It works fine using crossover version of wine, but has problems in version 0.9.41, (communicates but with a lot of errors making it unusable). To get round this I use "ser2net" and access serial ports via tcp ie; in /etc/ser2net.conf 2000:telnet:0: /dev/ttyS0:9600 8DATABITS NONE 1STOPBIT 2001:telnet:0: /dev/ttyS0:19200 8DATTABITS NON 1STOPBIT 2002:telnet:0: /dev/ttyS1:9600 8DATABITS NONE 1STOPBIT 2003:telnet:0: /dev/ttyS1:19200 8DATTABITS NON 1STOPBIT This makes ttyS0 available as localhost:2000 or localhost:2001 depending on which baud rate you want.