Please update to wine-1.5.6, then try this recipe: rm -rf ~/.wine rm -f winetricks wget http://winetricks.googlecode.com/svn/trunk/src/winetricks sh winetricks dotnet11 dotnet20 gdiplus vcrun2008 export GC_DONT_GC=1 Then try installing the app. This recipe is from http://appdb.winehq.org/objectManager.php?sClass=version&iId=23486 and might not be complete. See also the sticky at the top of this forum re ubuntu 12.04 problems, and http://appdb.winehq.org/appview.php?iVersionId=3754 for dotnet20 tips.