Wineskin issues are best reported to the Wineskin website... http://wineskin.doh123.com/ its considered off topic here. to address the issues quickly, but don't reply here... 1. this is Xinput2 problems... try an engine that doesn't have xinput2 enabled. 2. no idea.. would need to know GPU differences, Wine version, etc... 3. might be their firewall pop up in the background... they can try Cmd+Opt+A to knock it out of the fullscreen mode to see.
