I always buy Asus mobos and they always have a serial header. The adapter you need is available from cables2go for about $10. My department always buys from Dell and they always come with the serial port DB9 port on the back. So for me, it hasn't been a problem using my serial hardware synth. -----Original Message----- From: Speakup [mailto:speakup-bounces@xxxxxxxxxxxxxxxxx] On Behalf Of acollins at icsmail.net Sent: Wednesday, December 12, 2012 4:26 AM To: Speakup is a screen review system for Linux. Subject: Re: Are the days of hardware synths and speaking from boot numbered? Well, they may be, but not quite yet. As John Covici pointed out, you can get cables and brackets to extend the serial headers on your mother board, if it has them. On the other hand, if you have an old isa card, and are in the market to buy a new computer, there are still companiesout there that make computers with both isa and pci slots, you just have to look for them. One that I found while doing a search is Nixsys Open Systems. Their web site is nixsys.com, where you will find a link for isa slot computers. They come in both short tower and rack mount configurations. Hope this helps. Gene _______________________________________________ Speakup mailing list Speakup at linux-speakup.org http://linux-speakup.org/cgi-bin/mailman/listinfo/speakup