Don't know if this helps, but I am running opensuse 12.1 with KDE 4.7.2; it is using alsa drivers and the sound works fine in Wine. I just upgraded from 11.4 where I had Civ4 installed in Wine and the sound worked just fine. I didn't do anything to make it so, I just installed Civ4 and mods just like I would in Windows and it worked. Sure it will work in 12.1 also.
