You'll know for certain that you have x11 installed if you go to your /applications/utilities folder and see x11. I'd recommend dragging it to your dock and launching it before launching wine. On Tiger, I think this is required. You probably also have to add a display variable to the .profile file in your home directory. Assuming you haven't done much in macports, this should work: Code: export PATH=/opt/local/bin:/opt/local/sbin:$PATH export DISPLAY=:0.0 Most of this is actually from the macports wiki: https://trac.macports.org/wiki/InstallingMacPorts Hope that helps.