My search obviously sucked! I found this thread (http://forum.winehq.org/viewtopic.php?t=13343) and the first response hinted me to what fixed my PS: cd ~/.wine/drive_c/Program\ Files/Adobe/Adobe\ Photoshop\ CS5/ mv msvcp90.dll msvcp90.dll.bak mv msvcr90.dll msvcr90.dll.bak It now launches and works as before! I am not sure what may have been in the wine upgrade that broke it, but that is what worked for me. Hopefully it may help others with the same problem.
