Sorry I have not make the sense clear! I want to run wine on MIPS architecture in Linux,not by Qemu. and the Qemu is also running on MIPS and just emulates the x86 instructions to MIPS. This is the basic scenario:the two kits are running independently on MIPS. What I want to do is to run x86 instructions in qemu and the winapi calls will be directed to wine .So the program flow is like this: win32 applications(X86) -> qemu (translate)-> wine (win32 api)