Sorry, i obviously define 'tweakls' differently. Reinstalled driver to the latest - 275.21. Created new prefix, installed google onto it and ran. On the first go it seemed somewhat ok. It worked, though with awful performance. After few minutes it crashed. On the second run i got the old 'Sketchup was unable to initialize OpenGL ! Please make sure you have installed..." error, which should go away with that GL registry tweak. Code: laur@laur-HP-Compaq-8510w:~$ WINEPREFIX="$HOME/.wine-google" wine '/home/laur/.wine-google/drive_c/Program Files/Google/Google SketchUp 8/SketchUp.exe' fixme:actctx:parse_depend_manifests Could not find dependent assembly L"Microsoft.VC80.MFCLOC" (8.0.50608.0) fixme:wininet:InternetSetOptionW Option INTERNET_OPTION_CONNECT_TIMEOUT (30000): STUB fixme:wininet:InternetSetOptionW INTERNET_OPTION_SEND/RECEIVE_TIMEOUT/DATA_SEND_TIMEOUT 30000 fixme:wininet:InternetSetOptionW INTERNET_OPTION_SEND/RECEIVE_TIMEOUT/DATA_SEND_TIMEOUT 30000 fixme:wininet:InternetSetOptionW INTERNET_OPTION_CONNECT_RETRIES 0 Intrinsic Alchemy v3.3 Beta-0702 (Dynamic/Release) Built by <unknown> on Fri Jul 2 00:00:00 2010 PS i have misunderstood prefixes the whole time. Is there any difference when i 1) install program in different prefix using something like Code: WINEPREFIX="$HOME/.wine-second" wine '/home/laur/Downloads/PROGRAM_installer.exe' or 2) run the program, which is installed onto default prefix, under different prefix: Code: WINEPREFIX="$HOME/.wine-second" wine '/home/laur/.wine/drive_c/Program Files/PROGRAM.exe' PPS DanKegel told two different wine versions can be used. According to wiki, i'd have to compile new from source code in order to achieve this. Is there any way i could install my already compiled wine from .deb file next to this version?