Haven't seen one. 1) It's tempting to recommend a stripped-down ubuntu as the base environment, if only because that way you can be sure of security updates. 2) it depends on the app. Some apps expect to be able to write to their install directory, for instance. You can do tricks like using a copy-on-write filesystem or aufs mount, and throw away the changes after each run. You can also make all the files be symlinks to readonly files, in those directories that the game requires to be writeable. 3) You can set WINEPREFIX, use a symlink for ~/.wine, or you can set ~/.wine/dosdevices/c: to be a symlink to somewhere. Good luck, and keep us posted on your progress!