Ok, it happened again a couple of times today. I started a new game, so I'm wondering if it has something to do with this. Meanwhile, here are the results of the commands you both have suggested. xavier@xavier ~ $ ps -ef | grep wine xavier 2535 1 4 20:48 ? 00:01:00 /usr/local/bin/wineserver xavier 2541 2539 0 20:48 ? 00:00:00 C:\windows\system32\winedevice.exe MountMgr xavier 2862 2855 0 21:09 pts/1 00:00:00 grep --colour=auto wine typing "top" reveals that MassEffect.exe eats 40% of my cpu, hence two cores out of 4. Makes sense to me. After killing the program, xavier@xavier ~ $ ps -ef | grep wine xavier 3043 2855 0 21:15 pts/1 00:00:00 grep --colour=auto wine The keyboard slowdown still happens in X after killing the app. Hence it seems like an X bug to me. I will file something on the X bugzilla and report back if they ask anything.