Yes, you can do this. winetricks does this internally for a few verbs (with a function called w_override_app_dlls) but doesn't provide a way for you to do it yourself. But you can do it with winecfg; just select the application when you start winecfg, and then set the overrides. See http://wiki.winehq.org/winecfg (Of course, Wine's eventual goal is to get rid of the need for all overrides, but it might be a while before we get there.)
