Are either of you missing an installation of X11? If you install Apple's X11 (not recommended) or XQuartz X11 you should get a universal binary libfreetype either in /usr/X11/lib or /opt/X11/lib You will need to add those paths to your environment before you configure: CFLAGS="-I/opt/X11/include" LDFLAGS="-L/opt/X11/lib" ./configure --prefix=...