On my gentoo 64bit with wine 1.3.4 all works fine I did: applyed patch for dlls/d3d9/directx.c added two keys to registor in HKEY_CURRENT_USER\Software\Wine\Direct3D first one DirectDrawRenderer = gdi second one VideoMemorySize = 512 Installed fallout with it's own directx installed patches and DLC patched it with nodvd play well But after upgrade to 1.3.5 fallout won't run at all.