Hello. I am hoping someone can help with a problem I am having. I am running the Windows folding@home client through wine. This app is very load intensive and performs many scientific calculations. It consumes 100% of all six cores in my system. However, I run it with a "nice" level of 19 so that it only uses idle cycles. Unfortunately, with this setup, my system consistently stutters or skips at random intervals (several times per minute). These micro-stutters cause my mouse to stop moving and media to stop playing, etc. The whole system freezes for a fraction of a second each time. I do not believe the Folding@home client itself is responsible since the problem does not occur on Windows with the same executable. I have tried wine 1.2.1 and 1.3.5 on Ubuntu 10.04 and 10.10 with the same results. No other program on my system - even other load intensive applications - cause this issue. I am happy to provide any other additional information that would be helpful. This is very annoying and hinders my normal work. Any help is greatly appreciated!