I've already read through bug 11811 (http://bugs.winehq.org/show_bug.cgi?id=11811) so I know a patch was offered about two years ago for Wine automatically recognizing the com* symlinks in ~/.wine/dosdevices. Is there any hope that this will be functional soon? I am trying a utility that needs to access the serial ports but there are none shown available in its ports dialog. I do have symlinks pointing to the proper device files, but the ports do not show in Wine's regedit as they do on a WinXP machine's regedit. So I think this is deeper than an application specific issue.
