I am not so interested in ChemSketch, eventhough it seems to be running ok, I have not tried to use it yet. Unfortunately it seems to be loading together with the NMR processor and may this is what causes all the grief. P.S.> This is the page I have seen, I know that it is quite old and that the version of Wine get some stuff right and others that would run upon upgrade will not run anymore. I will have a look and will let you know