Did you do anything special that sets your DLLs to native and then builtin, and do you want to revert these? Because if not, you don't have to set up a thing - builtin,native is already the default. Anyway, winetricks can do this: Code: alldlls=builtin Force use of builtin dlls (even if loaded with absolute path) (except for msvcp80 and d3dx9_*) alldlls=default Remove all DLL overrides