By running winecfg and going to the Graphics tab and checking "Emulate a virtual desktop" and selecting the correct resolution I am able to maintain World of Warcraft running in full screen even when switching desktops. System: wine-1.2-rc6 on Ubuntu 10.04 64-bit This is a little annoying since running other wine applications will essentially fill the entire desktop space. Not sure how this will effect gameplay performance yet, but so far so good.