I've been running WoW on linux for quite some time now and found that any time they go through a new patch etc you can no longer start WoW from the launcher. I am not 100% why or how but if you browse to your WoW folder on your wine drive such as c:\program files\world of warcraft it keeps locking all the folders and won't let you access them The only way i have found around this is to never use the launcher and start the game directly from the WoW.exe file right in the WoW folder.
