> I just discovered... if I write my own script to launch wineprefixcreate... and have it manually create the wineprefix folder, drive_c folder, and dosdevices with the symlinks to drive_c and root... then after that calling wineprefixcreate works fine.... also automatically creating the prefix from just running an app works too after that. Maybe its just something faulty in the creation code on OSX? http://wiki.winehq.org/wineprefixcreate "Note: wineprefixcreate is deprecated and should not be needed anymore." Should all be automatic now, with wineboot taking care of the heavy lifting.