IMO the only thing you should use is a terminal / console. No GUI crap. Some pages you should imperatively read.. http://www.winehq.org/docs/wineusr-guide/index http://wiki.winehq.org/ Useful registry keys (eg. Video Memory) : http://wiki.winehq.org/UsefulRegistryKeys To remove a prefix (if for example the prefix is located at /home/*your user name*/.wine) Code: rm -R /home/*your user name*/.wine