Very odd. I can believe the sound problems... could just be an issue with the new ALSA and/or kernel. The odd part is that you only see the OSS driver when building Wine from source. That definitely sounds like you're missing some -dev package. I build wine from source every day, and I have all the options and they all work. Does 'sudo apt-get build-dep wine' tell you that you need any new dev packages? I know that I had to grab a few new ones after the upgrade to karmic. I'm running the 64-bit version, btw: Linux mars 2.6.30-5-generic #6-Ubuntu SMP Mon May 11 20:46:57 UTC 2009 x86_64 GNU/Linux