Thank You Here is terminal output. [user@localhost ~]$ su Password: [root@localhost user]# wine start 'd:/office12/onenote.exe' fixme:exec:SHELL_execute flags ignored: 0x00000500 fixme:actctx:parse_depend_manifests Could not find dependent assembly L"Microsoft.VC80.CRT" [root@localhost user]# err:module:import_dll Library MSVCR80.dll (which is needed by L"D:\\Office12\\ONENOTE.EXE") not found fixme:actctx:parse_depend_manifests Could not find dependent assembly L"Microsoft.VC80.CRT" err:module:import_dll Library MSVCR80.dll (which is needed by L"D:\\Office12\\ONMain.DLL") not found err:module:import_dll Library ONMain.DLL (which is needed by L"D:\\Office12\\ONENOTE.EXE") not found err:module:LdrInitializeThunk Main exe initialization for L"D:\\Office12\\ONENOTE.EXE" failed, status c0000135 I really appreciate this help.