The problem was not the WINE update, sorry for the post here. Since I did post I am adding the solution in case someone runs into this later and searches for it. The other update my system got along with the new Wine version was to xorg x-11. I had checked to be sure it was not the same update number that broke things last week and so assumed my problem was the WINE update. What happened was that the xorg update removed a line in /ect/X11/xorg.conf. In the Files section I had to add back in the line: ModulePath "/usr/lib64/xorg/modules/extensions/fglrx" Input works fine now, in game and out.