OK, I tried wineboot -r; didn't do anything. There is a Runonce key, which points to the original SETUP.EXE. Running that, both with and without a previous wineboot -r, did nothing. The setup program is apparently not writing all of the files it needs to its temporary directory. No telling why, but that seems to be the problem. So I think we'll just have to chalk this up to one that isn't going to work.