Craig73 wrote: > a) I assume that multiple prefixes can be run in Wine because it is popular to install apps into seperate wineprefixes to isolate them... so I assume I can run these two apps at the same time with no risk of corruption? [Is this correct?] Yes. Craig73 wrote: > b) So if I've copied my .wine folder to some shared read-only location, then symlinked to my local .folder all the read-only shared stuff, and the files that need to be modified (specifically profile/username, user.reg, and perhaps temp) are located in my local .wine folder, then why would I expect any corruption? [Note: I was wondering if MSOCache, DLLCache, Spool need to be local and user modifiable as well. I'm not sure why the userdef.reg the default user needs to be user modifiable.] Depends on what m$ does with them. I would imagine some stuff checks if files needs to be upgraded by checking the files. But also all m$' patches modify registry. So you might endup with "half-installed" patch. But you talking about read-write access to files not read-only.