http://wiki.winehq.org/UsefulRegistryKeys I recommend using the DirectDrawRenderer and set it to opengl. I also recommend setting your cards video memory under the VideoMemorySize key. I've messed with "RenderTargetLockMode" and chose textex for my nvidia card, I really couldn't find any appreciable difference between the options, I think one option slightly lowered my fps when I was testing them. Here is also a ton of info on just running wine and wow: http://www.wowwiki.com/Wine_(software) As other posters have mentioned before, to access files it says you don't have permission to, its better to use 'sudo'. For instance, to open a file in ubuntu: sudo gedit <path to file> sudo gedit myFile sudo gedit /etc/X11/xorg.conf Under kubuntu, use 'kate' sudo kate <path to file> "sudo" runs the single command with root privileges. Be careful when modifying xorg.conf, make a backup. Also, switching to linux with an ati graphics card was a poor choice. If it can be helped, buy a nvidia card. Also, when upgrading to 8.10, the restricted drivers offered by ubuntu were crap for nvidia, I had to install beta drivers manually (which is fun, because every kernel patch breaks them). Hopefully someone with knowledge of ati, wine and wow can help.