I am having the same issue. I am running os x 10.5.5 with XQuartz 2.3.1 and Darwine 1.1.7. (I also tried 1.0.1 with same issues) The installers both ran successfully, but I am not able to run any of the Sample WinLib Applications. They all crash with various error log messages, but all have this in common: err:module:attach_process_dlls "gdi32.dll" failed to initialize, aborting here's the full log message: err:module:attach_process_dlls "gdi32.dll" failed to initialize, aborting err:module:LdrInitializeThunk Main exe initialization for L"Z:\\Applications\\Darwine\\Sample WineLib Applications\\winecfg.exe" failed, status c0000005 I get the same message for notepad.exe and the others as well. Any ideas? As I said, I tried darwine 1.0.1 as well.