I have removed the nvidia drivers (yum remove kmod-ndivida) and also removed mesa-libGL* (yum remove mesa-libGL*) which removed a lot of libraries and quite a few apps. I have reinstalled kmod-nvidia and all the recommended dependencies from Wine HQ (for Fedora) and the same problem still exists. $ ./configure -v | grep -i gl checking jpeglib.h usability... yes checking jpeglib.h presence... yes checking for jpeglib.h... yes checking for GL/gl.h... yes checking for GL/glx.h... yes checking for GL/glext.h... yes checking for GL/glu.h... yes checking for up-to-date OpenGL version... yes checking for -lGL... not found checking for -lGL... not found checking for -lGLU... libGLU.so.1 checking for freetype/ftglyph.h... yes config.status: creating dlls/glu32/Makefile config.status: creating dlls/opengl32/Makefile config.status: creating dlls/opengl32/tests/Makefile configure: WARNING: No OpenGL library found on this system. OpenGL and Direct3D won't be supported. I'm due to do a rebuild on my laptop as I want to enable encryption so I'll see if that resolves the problem, otherwise I suppose I'll just continue to use Wine using the RPMs as OpenGL does work OK that way. Thanks for all your suggestions. Andrew