Please don't try to link wine to a real windows installation. You might end up breaking both of them without solving anything. The best you can do is to read the appdb page for the software you are using, it may have some explanations on how to solve your problems. If there is no information or no corresponding page on the appdb or it doesn't solve your problem, come back here and give us the name of this application and an official site where we can download it (if any), the wine version you are using and your linux distribution (or any other OS you are using) After going through this, we might be able to start asking you for the right information that can help us help you. Note : Try upgrading wine to a more recent version if possible, lots of problems are solved at each new release.