This is what I get (it is a different computer than the one from work, but the same problem): robin@robin-desktop:~$ wine "C:\Program Files\Materialise\Mimics 11.1\Mimics.exe" preloader: Warning: failed to reserve range 00000000-60000000 err:dosmem:setup_dos_mem Cannot use first megabyte for DOS address space, please report fixme:win:UpdateLayeredWindow (0x20024,0x1e8,0x7f21fa30,0x7f21fa28,0x200,0x7f21fa20,0x00000000,0x7f21fa18,2): stub! fixme:dwmapi:DwmIsCompositionEnabled 0x7f21f234 fixme:advapi:LookupAccountNameW (null) L"USERS" 0x7f03ab2c 0x7f21ee08 (nil) 0x7f21ee04 0x7f21ee00 - stub fixme:advapi:RegisterEventSourceW ((null),L"MatLicensing"): stub fixme:advapi:ReportEventW (0xcafe4242,0x0002,0x0000,0x00000000,(nil),0x0001,0x00000000,0x7f21ee58,(nil)): stub fixme:advapi:DeregisterEventSource (0xcafe4242) stub fixme:advapi:LookupAccountNameW (null) L"USERS" 0x7f03ab2c 0x7f21ee24 (nil) 0x7f21ee20 0x7f21ee1c - stub fixme:advapi:RegisterEventSourceW ((null),L"MatLicensing"): stub fixme:advapi:ReportEventW (0xcafe4242,0x0002,0x0000,0x00000000,(nil),0x0001,0x00000000,0x7f21ee74,(nil)): stub fixme:advapi:DeregisterEventSource (0xcafe4242) stub robin@robin-desktop:~$ I think that Wine loads fine, it just tries to do something that might be beyond its abilities, that triggers the error message and terminates the programme. If anyone could help, I would be glad!