Thanks, I mapped my iso mount point to a drive letter in winecfg. I then tried to execute the following command: wine e:\setup.exe with the Current Directory out of the game's folder with Sim City 4 Deluxe but the installer program did not like the CD being outside the game's directory and wouldn't start (I think this is what happened anyway because when CD was in game directory it would work). I then tried Winefile and this worked. It would be good if someone could tell me how to not have the CD in the game's directory but still allow the game to execute, although I am happy with using winefile.