Now it works!! :D 8) I renamend the folders ".wine" and ".winetrickscache" and I first reinstalled wintricks with Code: sh winetricks vcrun6 corefonts (package "cabextract" required!) In order to avoid other issues I installed the gecko-engine too with: Code: wine iexplore http://www.google.com After that I reinstalled Photoshop CS and the activation worked fine. ;) thanks for your help, Stephan