> What, exactly, is the error message? COMM ERROR! "Error connecting to PLC! Error: Cannot access the comm port. The port may not be present or another app my be using it. Ext Error. " > If your app claims the port is busy it could be either an access > permission problem or that some other program is using it. setserial > reports "Device or resource busy" if the device is in use and "No such > file or directory" if the device file doesn't exist. It may be worth > running this dual command: > > ls -l /dev/ttyS*; sudo lsof | grep 'ttyS.' > > immediately before and after trying your Wine app. I tried this and get the same results before and after Code: root@interfor-debain:/home/electrician# ls -l /dev/ttyS*; lsof | grep 'ttyS.' crw-r--r-- 1 root dialout 4, 64 May 22 12:59 /dev/ttyS0 crw-rw---- 1 root dialout 4, 65 May 22 12:59 /dev/ttyS1 crw-rw---- 1 root dialout 4, 66 May 21 13:41 /dev/ttyS2 crw-rw---- 1 root dialout 4, 67 May 21 13:41 /dev/ttyS3