oh I forgot.. if you started X11.bin that way with say :55 display, in the terminal session your running Wine in you'd have to do something like this.. so it would draw in the right Xquartz instance. export DISPLAY=:55 wine myprogram.exe or Wine will say it cannot find a x server... or you could probably just /Applications/Utilities/Xquartz.app/Contents/MacOS/X11.bin :$DISPLAY and have it use whats already set, but I never tested that.. I like setting up stuff to run multiple X sessions, but most of the time I'm just using Wineskin, but thats sort of how I have it set up behind the scenes.