I already did (though I did do it manually, based on the configure output and the config.log error messages, rather than using a guide which might be outdated and/or not apply to my setup). The remaining "feature not enabled" messages from the end of the 32-bit side of the Wine configure process are: Code: configure: OpenCL 32-bit development files not found, OpenCL won't be supported. configure: gstreamer-0.10 base plugins 32-bit development files not found, gstreamer support disabled configure: libgsm 32-bit development files not found, gsm 06.10 codec won't be supported. configure: WARNING: libjpeg 32-bit development files not found, JPEG won't be supported. These are all due to the relevant libraries not being available (in appropriate architectural configurations) via Debian. At a glance, none of them seem likely to be relevant to the problem at hand. This is with a configure command line of Code: ../../clean/configure --with-wine64=../wine64 in case it matters. Wine64 was built immediately prior to this build, with a command line of Code: ../../clean/configure --enable-win64 and the only feature listed as missing in that configuration is OpenCL.