Specifically, commit c4824ae7db418aee6f50f308a20b832e58e997fd triggers the problem. Reverting this change restores functionality. The device is an RME Multiface II, using the snd-hdsp driver. Expected behavior: Device plays sound normally Exhibited behavior: When a program attempts to open the device, the following ALSA lib error happens: ALSA lib pcm_direct.c:1169:(snd1_pcm_direct_initialize_slave) slave plugin does not support mmap interleaved or mmap noninterleaved access This change hasn't affected my other computers with less esoteric hardware, so probably the problem lies with the snd-hdsp driver, but the device is unusable without reverting that commit. I am available to test any patches for this issue. Thanks, J Woods