It seems that I have solved the issue by using nf_conntrack_ftp and redirecting "NEW,RELATED" traffic to squid: ftp_port 2121 intercept modprobe nf_conntrack_ftp ports=2121 iptables -t nat -A PREROUTING -p tcp --dport 21 -j REDIRECT --to-port 2121 iptables -t nat -A PREROUTING -p tcp -m state --state NEW,RELATED -j REDIRECT Thank you for your time. -- View this message in context: http://squid-web-proxy-cache.1019090.n4.nabble.com/Native-FTP-relay-connection-closes-after-cannot-assign-requested-address-error-tp4681208p4681332.html Sent from the Squid - Users mailing list archive at Nabble.com. _______________________________________________ squid-users mailing list squid-users@xxxxxxxxxxxxxxxxxxxxx http://lists.squid-cache.org/listinfo/squid-users