Now is ok, you need add "ulimit -n 65536' in you squid startup script. Thanks. -----Original Message----- From: Alfred Ding [mailto:Alfred.Ding@xxxxxxxxxxxx] Sent: 2013年1月14日星期一 09:51 To: squid-users@xxxxxxxxxxxxxxx Subject: Your cache is running out of filedescriptors Hi, My system is Ubuntu 12.04.1 LTS, it is ok running the squid (V3.1.19) comes with the OS, but it is not ok when I use the squid (V3.2.5) compiled from source, Follow is the configure: ./configure --prefix=/var/squid32 --enable-delay-pools --enable-gnuregex --disable-maintainer-mode --disable-dependency-tracking --disable-silent-rules --enable-inline --enable-async-io=8 --enable-storeio=ufs,aufs,diskd --enable-removal-policies=lru,heap --enable-delay-pools --enable-cache-digests --enable-underscores --enable-icap-client --enable-follow-x-forwarded-for --enable-basic-auth-helpers=LDAP,MSNT,NCSA,PAM,SASL,SMB,YP,DB,POP3,getpwnam,squid_radius_auth,multi-domain-NTLM --enable-ntlm-auth-helpers=smb_lm, --enable-digest-auth-helpers=ldap,password --enable-negotiate-auth-helpers=squid_kerb_auth --enable-external-acl-helpers=ip_user,ldap_group,session,unix_group,wbinfo_group --enable-arp-acl --enable-snmp --enable-esi --enable-zph-qos --enable-wccpv2 --disable-translation --with-filedescriptors=65536 --with-large-files --with-default-user=proxy --enable-linux-netfilter --enable-ssl --enable-ssl-crtd Could you have suggestion? Thanks, Alfred.