NEW TEAMS JOIN NETWORK TO MODEL PANDEMIC FLU, OTHER INFECTIOUS OUTBREAKS

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U.S. Department of Health and Human Services 
NATIONAL INSTITUTES OF HEALTH 
NIH News 
National Institute of General Medical Sciences (NIGMS)
http://www.nigms.nih.gov/

FOR IMMEDIATE RELEASE: Wednesday, February 1, 2006

CONTACT: Emily Carlson, 301-496-7301, carlsone@xxxxxxxxxxxxx

NEW TEAMS JOIN NETWORK TO MODEL PANDEMIC FLU, OTHER INFECTIOUS OUTBREAKS

Four new scientific teams joined an international research network
developing computer-based simulations of pandemic flu and other
infectious disease outbreaks, the National Institute of General Medical
Sciences (NIGMS), a component of the National Institutes of Health,
announced today.

The network is part of the Models of Infectious Disease Agent Study
(MIDAS), an ongoing NIGMS effort to use computer modeling techniques to
better understand the spread of contagious diseases and the potential
impact of public health measures. The results could aid health officials
and policymakers in developing preparedness plans for outbreaks that
occur naturally or deliberately.

The new research groups will receive a total of approximately $7.8
million over the next five years and will collaborate with four existing
MIDAS teams established in 2004.

"The MIDAS network has already demonstrated the power of applying
computer models to the study of disease spread and the effects of
various intervention strategies," said Jeremy M. Berg, Ph.D., NIGMS
director. "The new MIDAS teams expand the network's spectrum of
expertise and enhance its ability to develop robust models."

In addition to the individual research projects described below, the new
MIDAS teams will contribute to the network's pandemic influenza modeling
project. This project involves simulating outbreaks of a deadly flu
strain in different regions of the world and then evaluating the effects
of various intervention measures, such as vaccination or school
closures, on containing or slowing disease spread.

The new MIDAS awards will support researchers at:

-- The University of California, Irvine, and the Centers for Disease
Control and Prevention in Atlanta, Ga. This group will analyze past
transfers of flu from birds to people and model the effects of rapid
pathogen evolution on strategies for disease surveillance, prediction,
and control.

-- The Harvard School of Public Health in Boston, the University of Hong
Kong, the National Institute of Public Health and the Environment in the
Netherlands, and the University of Washington in Seattle. This team will
use mathematical models to explore mechanisms of transmission, evaluate
public health measures, and design methods for monitoring the early
stages of an outbreak in real time.

-- The University of Pennsylvania School of Veterinary Medicine in
Philadelphia and the University of Warwick in the United Kingdom. This
team will develop spatial and temporal models of infectious animal
diseases, particularly those like avian influenza that can cross species
barriers to infect people.

-- Harvard Pilgrim Health Care, Harvard School of Public Health, and
Brigham & Women's Hospital, all in Boston; Kaiser Permanente Northern
California in Oakland; and the National Institute of Infectious Diseases
in Argentina. This group will develop ways to identify new clusters of
emerging infectious diseases and track antimicrobial resistance in
hospitals and ambulatory settings. It also will optimize strategies for
using patient care data from large health systems in infectious disease
models. 

To arrange an interview with NIGMS Director Jeremy M. Berg, Ph.D.,
contact the NIGMS Office of Communications and Public Liaison at
301-496-7301. For more information about MIDAS, visit
http://www.nigms.nih.gov/Initiatives/MIDAS/.

NIGMS (http://www.nigms.nih.gov), a component of the National Institutes
of Health, supports basic biomedical research that is the foundation for
advances in disease diagnosis, treatment, and prevention.

The National Institutes of Health (NIH) -- "The Nation's Medical
Research Agency" -- includes 27 Institutes and Centers and is a
component of the U. S. Department of Health and Human Services. It is
the primary Federal agency for conducting and supporting basic,
clinical, and translational medical research, and it investigates the
causes, treatments, and cures for both common and rare diseases. For
more information about NIH and its programs, visit http://www.nih.gov.
  
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This NIH News Release is available online at:
http://www.nih.gov/news/pr/feb2006/nigms-01.htm.

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