2005 NIH DIRECTOR'S PIONEER AWARD RECIPIENTS ANNOUNCED

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U.S. Department of Health and Human Services 
NATIONAL INSTITUTES OF HEALTH 
NIH News 
NIH Office of the Director (OD) 
http://www.nih.gov/icd/od/

National Institute of General Medical Sciences (NIGMS) 
http://www.nigms.nih.gov/

FOR IMMEDIATE RELEASE: Thursday, September 29, 2005 

CONTACT: Ann Dieffenbach, 301-496-7301, dieffena@xxxxxxxxxxxxx; OD Office of
Communications and Public Liaison, 301-496-5787
  
2005 NIH DIRECTOR'S PIONEER AWARD RECIPIENTS ANNOUNCED 

National Institutes of Health Director Elias A. Zerhouni, M.D., today named
13 new recipients of the NIH Director's Pioneer Award. 

A key component of the NIH Roadmap for Medical Research, the Pioneer Award
supports exceptionally creative scientists who take innovative approaches to
major challenges in biomedical research. The award gives recipients the
intellectual freedom to pursue groundbreaking new research directions that
could have significant impact if successful but that, due to their novelty
or other factors, also have inherently high risks of failure. 

"The scientists we recognize with Pioneer Awards have far-ranging ideas that
hold the potential to make truly extraordinary contributions to many fields
of medical research," said Zerhouni. "The recipients reflect the talent and
diversity of the impressive group of scientists who competed for the award.
The strength of this group, and the willingness of a number of NIH
components to contribute funds to the program, led us to make nearly twice
as many awards as we originally planned. This speaks volumes about the
exciting opportunities that lie ahead, and we look forward to seeing where
the visionary concepts of our Pioneer Awardees lead." 

The 2005 awardees work in diverse areas, including neuroscience, genetics,
epidemiology, chemistry, stem cell biology, behavioral science, infectious
diseases, and technology development. Six of the 13 are women and more than
half are at relatively early stages of their careers (the associate
professor level or below). 

The new awardees, who will receive $500,000 in direct costs per year for
five years, are: 

-- Vicki L. Chandler, Ph.D., Regents' Professor of Plant Sciences and
Molecular and Cellular Biology at the University of Arizona in Tucson, who
studies the control of gene expression. 

-- Hollis T. Cline, Ph.D., a professor and director of research at Cold
Spring Harbor Laboratory in Cold Spring Harbor, N.Y., who studies neural
connectivity in the brain. 

-- Leda Cosmides, Ph.D., a professor of psychology at the University of
California, Santa Barbara, who applies evolutionary psychology to discover
the design of the human mind and brain. 

-- Titia de Lange, Ph.D., the Leon Hess professor and head of the Laboratory
of Cell Biology and Genetics at The Rockefeller University in New York City,
who studies chromosome caps called telomeres. 

-- Karl Deisseroth, M.D., Ph.D., an assistant professor of bioengineering
and psychiatry at Stanford University in Stanford, Calif., who develops and
employs new technology to probe neural circuits in the brain. 

-- Pehr A.B. Harbury, Ph.D., an associate professor in the Department of
Biochemistry at Stanford University School of Medicine in Stanford, Calif.,
who studies the chemical evolution of small molecules. 

-- Erich D. Jarvis, Ph.D., an associate professor in the Department of
Neurobiology at Duke University Medical Center in Durham, N.C., whose
research focuses on the molecular basis of vocal learning. 

-- Thomas A. Rando, M.D., Ph.D., an associate professor in the Department of
Neurology and Neurological Sciences at Stanford University School of
Medicine, who studies the role of stem cells in tissue repair and
regeneration. 

-- Derek J. Smith, Ph.D., a research associate in the Department of Zoology
at the University of Cambridge in Cambridge, England, and a research
scientist in virology at Erasmus Medical Center in Rotterdam, The
Netherlands, who uses mathematics to study the influenza virus and other
rapidly evolving infectious agents. 

-- Giulio Tononi, M.D., Ph.D., a professor in the Department of Psychiatry
at the University of Wisconsin-Madison Medical School, who studies the
neural basis of consciousness and the function of sleep. 

-- Clare M. Waterman-Storer, Ph.D., an associate professor in the Department
of Cell Biology at The Scripps Research Institute in La Jolla, Calif., who
studies how cells change shape and move. 

-- Nathan D. Wolfe, D.Sc., an assistant professor in the Department of
Epidemiology at the Johns Hopkins University Bloomberg School of Public
Health in Baltimore, Md., who studies the emergence of infectious diseases. 

-- Junying Yuan, Ph.D., a professor of cell biology at Harvard Medical
School in Boston, Mass., who will explore the possible existence of a novel
cellular mechanism that detects and removes misfolded, neurotoxic proteins. 

The announcement of the 2005 Pioneer Award recipients occurred at the first
annual NIH Director's Pioneer Award Symposium. This event featured
individual talks and a roundtable discussion by the inaugural group of
awardees, who were selected in September 2004. 

The newest Pioneer Award recipients were selected from 840 scientists who
underwent a streamlined but rigorous self-nomination and evaluation process
that began in March 2005. After NIH staff determined the eligibility of each
nominee, the first of three groups of distinguished outside experts
identified the most highly competitive individuals in the pool. The second
set of outside experts evaluated the 285 scientists in this group, focusing
on their innovativeness and creativity, the importance of the scientific
problem to be addressed, and the likelihood that the project's success would
have a high impact on biomedical research. The evaluators also considered
the appropriateness of the project for the Pioneer Award mechanism,
including the requirement that it be distinct from other research by the
investigator. These evaluators identified 20 scientists who were then
interviewed at NIH by the third group of outside experts. 

A final review was performed by the Advisory Committee to the Director, NIH,
which made funding recommendations to the NIH Director based on the
evaluations by the outside experts and programmatic considerations. 

More information on the 2005 NIH Director's Pioneer Award recipients is at
http://nihroadmap.nih.gov/pioneer/Recipients05.aspx. Details on the Pioneer
Award program, including the names of the outside evaluators for the 2005
awards, are at http://nihroadmap.nih.gov/pioneer. 

The NIH Roadmap is a series of far-reaching initiatives designed to
transform the nation's medical research capabilities and speed the movement
of research discoveries from the bench to the bedside. It provides a
framework of the priorities the NIH must address in order to optimize its
entire research portfolio and lays out a vision for a more efficient and
productive system of medical research. For more information about the NIH
Roadmap, please visit the Web site at http://nihroadmap.nih.gov.

The National Institutes of Health (NIH) -- "The Nation's Medical Research
Agency" -- includes 27 Institutes and Centers and is a component of the U.
S. Department of Health and Human Services. It is the primary Federal agency
for conducting and supporting basic, clinical, and translational medical
research, and it investigates the causes, treatments, and cures for both
common and rare diseases. For more information about NIH and its programs,
visit http://www.nih.gov.
  
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This NIH News Release is available online at:
http://www.nih.gov/news/pr/sep2005/od-29a.htm.

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