Modify packet without NAT

[public1020 <public1020@xxxxxxxxx>]

I have a simple nat configuration to forward certain access to a gateway:

iptables -t nat -A PREROUTING -p tcp -m set --match-set http_port dst,dst -j DNAT --to-destination XXX:80
iptables -t nat -A POSTROUTING -j MASQUERADE

Can I do that without nat? Just trying to avoid the "conntrack table full" issue.
Is there a non-stateful solution?