Cardiac Patients Take NASA Super Plastic to Heart

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May 6, 2009

Sonja Alexander 
Headquarters, Washington 
202-358-1761 
sonja.r.alexander@xxxxxxxx 

Chris Rink 
Langley Research Center, Hampton, Va. 
757-864-6786 
christopher.p.rink@xxxxxxxx 

RELEASE: 09-101

CARDIAC PATIENTS TAKE NASA SUPER PLASTIC TO HEART

WASHINGTON -- A NASA technology that was developed for an aerospace 
high-speed research program is now part of an implantable device for 
heart failure patients. 

NASA's Langley Research Center in Hampton, Va., created an advanced 
aerospace resin, named Langley Research Center's Soluble Imide, or 
LaRC-SI. It is highly flexible, resistant to chemicals, and 
withstands extreme hot and cold temperatures. The "super plastic" was 
determined to be biologically inert, making it suitable for medical 
use, including implantable devices. 

"One of the advantages of this material is that it lends itself to a 
variety of diverse applications, from mechanical parts and composites 
to electrical insulation and adhesive bonding," said Rob Bryant, a 
NASA Langley senior researcher and inventor of the material. 

In July 2004, NASA licensed the patented insulation technology to 
Medtronic Inc., a Minneapolis-based medical technology company. 
Medtronic Inc. incorporated the material into its Attain Ability 
left-heart lead, which the U.S. Food and Drug Administration recently 
approved. 

The use of this NASA-developed material in a medical implant is the 
latest in a long line of medical applications that have benefited 
from NASA technology. 

"Langley Research Center's Soluble Imide is an excellent example of 
how taxpayer investment in NASA materials research has resulted in a 
direct benefit beyond the aerospace sector by extending the quality 
of life through medical technology," Bryant said. 

Heart failure occurs when the heart muscle is unable to pump 
effectively to meet the body's need for blood and oxygen. It is a 
chronic and progressive condition that affects more than five million 
Americans and more than 22 million individuals worldwide. Cardiac 
resynchronization therapy, or CRT, is designed to coordinate the 
contraction of the heart's two lower chambers and improve the heart's 
efficiency to increase blood flow to the body. 

CRT devices, which are stopwatch-sized, are implanted into the chest 
and connected to the heart by leads, such as the Attain Ability 
left-heart lead. A lead is a special wire that delivers energy from a 
CRT to the heart muscle. Electrical impulses generated by CRTs 
resynchronize heartbeats and improve blood flow. 

The NASA insulation material makes possible the compact and flexible 
design of Medtronic's CRT lead, one of the thinnest left-heart leads 
available. Placing a lead in the heart is widely recognized by 
physicians as the most challenging aspect of implanting CRT devices. 
The narrow design allows physicians to choose between different sites 
on the heart to deliver optimal therapy. The lead is delivered by an 
inner catheter, a feature that helps physicians place the lead 
directly in difficult-to-reach areas of the heart. Clinical studies 
in the U.S. and Canada showed physicians were successful in placing 
the Attain Ability lead 96.4 percent of the time. 

The Langley Research Center's Soluble Imide was featured in Spinoff 
2008 -- NASA's annual premier publication featuring successfully 
commercialized NASA technology. For more than 40 years, the NASA 
Innovative Partnerships Program has facilitated the transfer of NASA 
technology to the private sector, benefiting global competition and 
the economy. Since 1976, Spinoff has featured 40 to 50 of these 
commercial products annually. 

In 1995, R&D Magazine selected the resin for an R&D 100 award as one 
of the top 100 technical innovations of the year. 

NASA Television is airing a Video File demonstrating the technology. 
For NASA TV streaming video, downlink and scheduling information, 
visit: 



http://www.nasa.gov/ntv 


For more information about Langley Research Center's Soluble Imide, 
visit: 



http://technologygateway.nasa.gov/Advanced_Materials.html 




and 




http://www.sti.nasa.gov/tto/Spinoff2008/hm_4.html 

	
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