Just my $0.02, unless things have changed recently, Speakup needs much better USB support. Speaking from the perspective of having a machine that doesn't have a serial port, and more and more machines are built that way now, USB is certainly the way to go. In the very near future, this will be entirely necessary, as motherboards with serial ports are becoming harder and harder to find, and most available plug-in serial ports are USB adapters. ~Kyle
